What are the symptoms of a positive ANA?

Clinical features that can emerge include but are not limited to fever, chills, joint swelling, nasal/oral ulcers, hair loss, severe dry eyes/dry mouth, and kidney disease. By itself, a positive ANA does not in any way mean you have an autoimmune disease or need treatment.

Can you have an autoimmune disease with a negative ANA?

A negative ANA result suggests the absence of many autoimmune diseases, but does not rule them out. Additional testing, for example with specific antibody tests, should be considered if clinically warranted (Table 2).

What does a negative ANA screen mean?

A negative test means that certain autoimmune diseases are less likely to be present. However, other tests may still be needed based on your symptoms. Some people with autoimmune diseases may get a negative test result for ANA but positive for other antibodies.

What medications can cause a negative ANA test?

Associated Medications
  • Sulfadiazine.
  • Hydralazine.
  • Procainamide.
  • Isoniazid.
  • Methyldopa.
  • Quinidine.
  • Minocycline.
  • Chlorpromazine.

Can vitamin D deficiency cause positive ANA?

Vitamin D deficiency may contribute to immune dysregulation resulting in the production of autoantibodies, in particular antinuclear antibodies (ANA) (6, 7).

Is a positive ANA test serious?

Results. The presence of antinuclear antibodies is a positive test result. But having a positive result doesn’t mean you have a disease. Many people with no disease have positive ANA tests — particularly women older than 65.

Can a positive ANA go away?

The new criteria require that the test for antinuclear antibody (ANA) must be positive, at least once, but not necessarily at the time of the diagnosis decision because an ANA can become negative with treatment or remission.